An Experimental Drug Slows Cancer's Circadian Clock

We are beginning to learn about the circadian rhythms that happen throughout the body.  Not just the rhythms that tell us when to sleep and when to wake up, but also when to eat, and as we are learning, even our cells have their own rhythm.  We've learned that when these rhythms are disrupted, like if we don't get regular sleep, or eat on a regular schedule, then our health is negatively impacted.

Scientists from USC Michelson Center for Convergent Bioscience and Nagoya University's Institute of Transformative BioMolecules (ITbM) are looking into whether disrupting the circadian rhythms of cancer cells can have an impact on their growth, or even kill those cells.

They tested a molecule named GO289, which interfered with the cell's circadian clock, slowed  down it's processes, and stop the cancer from growing - all without much impact on healthy cells.

Initial findings showed that GO289 could affect cancer cell metabolism, and other circadian-related functions that help the cancer to grow and spread.  The scientists are continuing their research, but are feeling optimistic about the potential of G0289.

Read more about these discoveries at Science Daily.